Recent Faculty Publications

Search the PubMed Database and Scopus Database for UC Chemistry Publications.

Alvarez, N. T.
; Buschbeck, E.; Miller, S.; et al. (2020): Carbon Nanotube Fibers for Neural Recording and Stimulation. ACS Appl Bio Mater 3, 9, 6478-6487. 

Alvarez, N. T.; Miller, P.; Haase, M. R.; et al. (2019): Tailoring physical properties of carbon nanotube threads during assembly. Carbon 144, 55-62. 

Gupta, P.; Tsai, K.; Ruhunage, C. K.; et al.; Alvarez, N.T. (2020): True Picomolar Neurotransmitter Sensor Based on Open-Ended Carbon Nanotubes. Anal Chem 92, 8536-8545. 

Huseinov, A.; Weese, B. L.; Brewer, B. J.; et al..; Alvarez, N.T. (2021): Near-electrode pH change for voltammetric detection of insoluble lead carbonate. Anal Chim Acta 1186, 339087. 

Rahm, C. E.; Torres-Canas, F.; Gupta, P.; et al..; Alvarez, N.T. (2020): Inkjet Printed Multi-Walled Carbon Nanotube Sensor for the Detection of Lead in Drinking Water. Electroanalysis 32, 1533-1545. 


McKenzie, T. J.; Rost, K.; Smail, S.; Mondain-Monval, O.; Brunet, T.; Ayres, N. (2022): Mechanically tunable PDMS-based polyHIPE acoustic materials. Journal of Materials Chemistry C 10, 6222-6226.
[Underlined Authors were undergraduate researchers]

McKenzie, T. J.; Smail, S.; Rost, K.; Rishi, K.; Beaucage, G.; Ayres, N. (2021): Multi-layered polymerized high internal phase emulsions with controllable porosity and strong interfaces. Polymer 231, 124116.
[Underlined Authors were undergraduate researchers]

Chimala, P.; Perera, M. M.; Wade, A.; McKenzie, T.; Allor J.; Ayres, N. (2021): Hyperbranched polymer hydrogels with large stimuli-responsive changes in storage moduli and peroxide-induced healing. Polymer Chemistry 12, 4384-4393.
[Underlined Authors were undergraduate researchers]

Perera, M. M.; Chimala, P.; Elhusain-Elnegres, A.; Heaton, P.; Ayres, N. (2020): Reversibly Softening and Stiffening Organogels Using a Wavelength-Controlled Disulfide-Diselenide Exchange. ACS Macro Letters 9, 1552-1557.  [Underlined Authors were undergraduate researchers]

McKenzie, T. J.; Heaton, P. S.; Rishi, K.; Kumar, R.; Brunet, T.; Beaucage, G.; Mondain-Monval, O.; Ayres, N. (2020): Storage moduli and porosity of soft PDMS PolyMIPEs can be controlled independently using thiol−ene click chemistry. Macromolecules 53, 3719-3727.   [Underlined Authors were undergraduate researchers]

E. Kliuchnikov, E. Klyshko, M. S.Kelly, A. Zhmurov, R. I. Dima, K. A. Marx, V. Barsegov, "Microtubule assembly and disassembly dynamics model: Exploring dynamic instability and identifying features of Microtubules’ Growth, Catastrophe, Shortening, and Rescue", Comp. Struct. Biotech. J., 20, 953-974 (2022). 

L. Szatkowski, R. A. Varikoti, and R. I. Dima, "Modeling the Mechanical Response of Microtubule Lattices to Pressure", J. Phys. Chem. B 125, 5009–5021 (2021). 

M. Damre, A. Dayananda, R. A. Varikoti, G. Stan and R. I. Dima, "Factors Underlying Asymmetric Pore Dynamics of Disaggregase and Microtubule Severing AAA+ Machines", Biophys. J. 120, 1-18 (2021).


GRILLO, TONY (new faculty arriving Fall '22)
Iron Status Influences Mitochondrial Disease Progression in Complex I-Deficient Mice
Grillo, A.S.
; Kelly, C.; Ha, V.T.; Bodart, C.M.; Huff, S.; Couch, R.K.; Herrel, N.T.; Kim, H.D.; Zimmermann, A.O.; Pan, Y.-C.; Shattuck, J.; Kaeberlein, M. BioRXiv 2021

PKC Downregulation upon Rapamycin Treatment Attenuates Mitochondrial Disease
Martin-Perez, M.*; Grillo, A.S.*; Ito, T.; Valente, A.S.; Han, J.; Entwisle, S.; Huang, H.Z.; Kim, D.; Yajima, M.; Kaeberlein, M.; Villain, J. Nat. Metab. 2020, 2, 1472-1481. 

Small Molecule Ion Channel Restores Host Defences in Cystic Fibrosis Epithelia
Muraglia, K.A.; Chorghade, R.S.; Kim, B.R.; Tang, X.X.; Shah, V.S.; Grillo, A.S.; Daniels, P.N.; Cioffi, A.G.; Karp, P.H.; Zhu, L.; Welsh, M.J.; Burke, M.D. Nature 2019, 567, 405-408. 

Restored Iron Transport by a Small Molecule Promotes Absorption and Hemoglobinization in Animals
Grillo, A.S.
; SantaMaria, A.M.; Kafina, M.D.; Cioffi, A.G.; Huston, N.C.; Han, M.; Seo, Y.A.; Yien, Y.Y.; Nardone, C.; Menon, A.V.; Fan, J.; Svoboda, D.C.; Anderson, J.B.; Hong, J.D.; Nicolau, B.G.; Subedi, K.; Gewirth, A.A.; Wessling-Resnick, M.; Kim, J.; Paw, B.H.; Burke, M.D. Science 2017, 356, 608-616. doi: 10.1126/science.aah3862


Ott, J. C.; Bürgy, D.; Guan, H.; Gade, L. H."3d Metal Complexes in T-Shaped Geometry as a Gateway to Metalloradical Reactivity.Acc. Chem. Res. 2022, 55, 857-868.

Collett, J. D.; Krause, J. A.; Guan, H. "Nickel Hydride Complexes Supported by Pyrrole-Derived Phosphine Ligand.Organometallics 2022, 41, 345-353.

Ekanayake, D. A.; Chakrabory, A.; Krause, J. A.; Guan, H. "Hydrogenation Reactions Catalyzed by HN(CH2CH2PR2)2-Ligated Copper Complexes." Inorg. Chem. Front. 2021, 8, 4634-4649.

Dai, H.; Li, W.; Krause, J. A.; Guan, H. "Experimental Evidence of syn H-N-Fe-H Configurational Requirement for Iron-Based Bifunctional Hydrogenation Catalysts.Inorg. Chem. 2021, 60, 6521-6535.


A Comprehensive Review: Development of Electrochemical Biosensors for Detection of Cyanotoxins in Freshwater, V. Vogiazi, A. de la Cruz, S. Mishra, V. Shanov, W. R. Heineman, D. D. Dionysiou, ACS Sens., 4, 1151-1173, 2019

Electrochemical Affinity Assays/Sensors:  Brief History and Current Status, K.R. Wehmeyer, R.J. White, P.T. Kissinger, W.R. HeinemanAnnual Review of Analytical Chemistry, 14, 109-131, 2021.

Editors’ Choice –Review–From Polarography to Electrochemical Biosensors:  The 100-Year Quest for Selectivity and Sensitivity, William R. Heineman, Peter T. Kissinger, Kenneth R. Wehmeyer,  Journal of the Electrochemical Society, 168 (11), 116504, 2021.

Spectroelectrochemistry Using Optically Transparent Electrodes – Ted Kuwana and the Early Years, William R. Heineman, Nicholas Winograd, William B. Jensen, Electroanalysis, 33, 1-9, 2021.



Prof. Jiang and his group publish their recent work in JACS on Perfluorooctanoic Acid Degradation (

Wang, X.; Chai, J.; Zhang, S.; Chen, B.; Chaturvedi, A.; Cui, G.; Jiang, J.* “Insights into Indigo K+ Association in a Half-Slurry Flow Battery,” ACS Energy Lett. 2022, 7, 1178–1186. 

Sinha, S.; Williams, C. K.; Jiang, J.* “Outer-Coordination Sphere in Multi-H+/Multi-e– Molecular Electrocatalysis,” iScience 2022, 25, 103628. 

Wang, X.; Lashgari, A.; Chai, J.;*  Jiang, J.* “A Membrane-Free, Aqueous/Nonaqueous Hybrid Redox Flow Battery,” Energy Storage Mater. 202245, 1100–1108. 

Wang, X.; Chai, J.; Devi, N.; Lashgari, A.; Chaturvedi, A.; Jiang, J.* “Two-Electron-Active Tetracyanoethylene for Application in Nonaqueous Redox Flow Batteries,” J. Mater. Chem. A 2021, 9, 13867–13873.  

Williams, C. K.; McCarver, G. A.; Lashgari, A.; Vogiatzis, K. D.;* Jiang, J.* “Electrocatalytic Dechlorination of Dichloromethane in Water Using a Heterogenized Molecular Copper Complex,” Inorg. Chem. 2021, 60, 4915–4923. 



Hammel, M.; Rashid, I.; Sverzhinsky, A.; Pourfarjam, Y.; Tsai, M-S.; Ellenberger, T.; Pascal, J. M. Kim, I-K.; Trainer, J. A.; Tomkinson, A. E. (2021): An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIa within a flexible DNA repair complex.  Nucleic Acids Research, 49 (1), 306-321.

Houl, J. H.; Ye, Z.; Brosey, C. A.; et al; Kim, I-K. (2019): Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nature Communications, 10, Article number: 5654.

Pourfarjam, Y.; Ma, Z.; Kurinov, g.; Moss, J.; Kim, I-K. (2021): Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 reveals the basis of metal selectivity and different roles for the two magnesium ions.  J. Biological Chemistry, 296, 100692.

Kasson, S.; Dharmapriya, N.; Kim, I-K. (2021): Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes.  PLoS ONE, 16(6):e0254022.

Pourfarjam, Y.; Ventura, J.; Kurinov, I.; Cho, A.; Moss, J.; Kim, I-K. (2018): Structure of human ADP-ribosyl-acceptor hydrolase 3 bound to ADP-ribose reveals a conformational switch that enables specific substrate recognitiion. J. Biological Chemistry, 293 (32), 12350-12359.


D'Ascenzo, L.; Popova, A. M.; Abernathy, S.; Sheng, K.; Limbach, P. A.; Williamson, J. R. (2022): Pytheas: a software package for the automated analysis of RNA sequences and modifications via tandem mass spectrometry.  Nature Communications, 13:2424.

Kelley, M.; Paulines, M. J.; Yoshida, G.; Myers, R.; Jora, M.; Levoy, J. P.; Addepalli, B.; Benoit, J. B.; Limbach, P. A. (2022): Ionizing radiation and chemical oxidant exposure impacts on Cryptococcus neoformans transfer RNAs.  PLoS ONE, 17(3).

Kelley, M.; Uhran, M.; Herbert, C.; Yoshida, G.; Watts, E. R.; Limbach, P. A.; Benoit, J. B. (2022): Abundances of transfer RNA modifications and transcriptional levels of tRNA-modifying enzymes are sex-associated in mosquitoes.  Insect Biochemistry and Molecular Biology, 143, 103741.

Limbach, P. A., et al. (2021): Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors. Nature Cancer, 2, 611-628.

Fasnacht, M.; Gallo, S.; Sharma, P.; Himmelstob, M.; Limbach, P. A.; Willi, J.; Polacek, N. (2021): Dynamic 23S rRNA modification Ho5C2501 benefits Escherichia coli under oxidative stress.  Nucleic Acids Research, 50(1), 473-489.

Copper-Catalyzed Difluoromethylation of Alkyl Halides Enabled by Aryl Radical Activation of Carbon–Halogen Bonds, Cai, A.†; Yan, W.†; Wang, C., Liu, W.Angew. Chem. Int. Ed. 2021, 60, 27070

Aryl Radical Activation of C - O Bonds: Copper-Catalyzed Deoxygenative Difluoromethylation of Alcohols, Cai, A†.; Yan, W.†; Liu, W.J. Am. Chem. Soc. 2021, 143, 9952

Copper-Catalyzed Carbo-Difluoromethylation of Alkenes via Radical Relay, Cai, A., Yan, W., Zeng, X., Zacate, B. S., Chao, T-H., Krause, A. J., Cheng, M-J., Liu, W.Nat. Commun. 2021, 12, 3272


Andersen, J.; Starbuck, H.; Current, T.; Martin, S.; Mack, J. (2021): Milligram-scale, temperature-controlled ball milling to provide an informed basis for scale-up to reactive extrusion. Green Chemistry, 23, 8501-8509.

Ortiz-Trankina, L.; Crain, J.; Williams, III, C.; Mack, J. (2020): Developing benign syntheses using ion pairs via solvent-free mechanochemistry.  Green Chemistry, 22, 3638-3642.

Andersen, J. M.; Starbuck, H. F. (with feedback from Mack. J.) (2021): Rate and yield enhancements in nucleophilic aromatic substitution reactions via Mechanochemistry.  J. Org. Chem., 86, 13983-13989.

Andersen, J.; Mack, J. (2018): Insights into Mechanochemical Reactions at Targetable and Stable, Sub-ambient Temperatures.  Angew. Chem. Int. Ed., 57, 13062-13065.

Andersen, J.; Mack, J. (2018): Mechanochemistry and organic synthesis: from mystical to practical. Green Chemistry, 20, 1435-1443.

Denlinger, K. L.; Carr, P.; Waddell, D. C.; Mack, J. (2020): A Recyclable, Metal-Free Mechanochemical Approach for the Oxidation of Alcohols to Carboxylic Acids.  Molecules, 25, 364.

Denlinger, K. L.; Ortiz-Trankina, L.; Carr, P.; Benson, K.; Waddell, D. C.; Mack, J. (2018): Liquid-assisted grinding and ion pairing regulates percentage conversion and diastereoselectivity of the Wittig reaction under mechanochemical conditions.  Beilstein J. Org. Chem, 14, 688-696.

Haley, R. A.; Ringo, J. M.; Hopgood, H.; Denlinger, K. L.; Das, A.; Waddell, D. C. (2018): Graduate Student Designed and Delivered: An Upper-Level Online Course for Undergraduates in Green Chemistry and Sustainability.  J. Chem. Educ., 95, 560-569.


Duane, B.; Pilling, J.; Saget, S.; Ashley, P.; Pinhas, A. R.; Lyne, A. (2022): Hand hygiene with hand sanitizer versus handwashing: what are the planetary health consequences? Environmental Science and Pollution Research, 30, xxxx.

Pinhas, A. R. (2021): Advantages and disadvantages of using the answer-until-correct multiple-choice test format for a class of non-STEM majors.  J. Chem. Ed., 98, 6, 2128-2131.

Phung, C.; Tantillo, D. J.; Hein, J. E.; Pinhas, A. R. (2018): The mechanism of the reaction between an aziridine and carbon dioxide with no added catalyst. J. Phys. Org. Chem., 31:e3735, 7 pgs.


Cryan, M. T.; Li, Y.; Ross, A. E. (2022): Sustained delivery of focal ischemia coupled to real-time neurochemical sensing in brain slices. Just Accepted. Lab on a Chip.

Keller, A. L.; Quarin, S. M.; Strobbia, P.; Ross, A. E. (2022):  Platinum nanoparticle size and density impacts purine electrochemistry with fast-scan cyclic voltammetry.  J. Electrochem. Soc., 169, 046514. 

Li, Y.; Jarosova, R.; Weese-Myers, M. E.; Ross, A. E. (2022): Graphene-fiber microelectrodes for ultrasensitive neurochemical detection. Analytical Chemistry, 94 (11), 4803-4812. 

Li, Y.; Keller, A. L.; Cryan, M. T.; Ross. A. E. (2021): Metal nanoparticle modified carbon-fiber microelectrodes enhance ATP surface interactions with fast-scan cyclic voltammetry. ACS Measurement Science Au (invited), 2(2), 96-105.

Lim, G. N.;Regan, S. L.;  Ross, A. E. (2020): Subsecond spontaneous catecholamine release in mesenteric lymph node ex vivo. Journal of Neurochemistry, 155(4), 417-429.

Steven Quarin, Pietro StrobbiaRecent Advances Towards Point-Of-Care Applications of Surface-Enhanced Raman Scattering Sensing, Frontiers in Chemistry, 2021, 9, 714113

Pietro Strobbia, Vanessa Cupil-Garcia, Bridget M Crawford, Andrew M Fales, T Joshua Pfefer, Yang Liu, Martin Maiwald, Bernd Sumpf, Tuan Vo-Dinh, Accurate in vivo tumor detection using plasmonic-enhanced shifted-excitation Raman difference spectroscopy (SERDS)Theranostics, 2021, 11(9), 4090

Pietro Strobbia, Yang Ran, Bridget M Crawford, Vanessa Cupil-Garcia, Rodolfo Zentella, Hsin-Neng Wang, Tai-Ping Sun, Tuan Vo-Dinh, Inverse Molecular Sentinel-Integrated Fiberoptic Sensor for Direct and in SituDetection of miRNA TargetsAnalytical chemistry, 2019, 91(9), 6345

Bridget M Crawford*, Pietro Strobbia*, Hsin-Neng Wang, Rodolfo Zentella, Maxim I Boyanov, Zhen-Ming Pei, Tai-Ping Sun, Kenneth M Kemner, Tuan Vo-Dinh, Plasmonic nanoprobes for in vivo multimodal sensing and bioimaging of microRNA within plantsACS applied materials & interfaces, 2019, 11(8), 7743



Slonecker, P.; Vonderheide, V. P. (2022): Qualitative Analysis of Acetophenone, Naphthalene, and Hexadecane by GC-Triple-Quad-MS Using MRM. J. Chem. Educ., 99, 3, 1460-1467.

Vonderheide, A. P.; Sunny, C. E.; Koenig, K. (Accepted): Development of a Concept Inventory for Nursing GOB Chemistry.  Submitted to Journal of STEM Education, Accepted, January 2022.

Vonderheide, A. P. (2021): An Exercise in General, Organic and Biochemistry to Stress the Importance of Math Mindfulness and Critical Thinking to Nursing Students. Chemical Educator, 26, 1-4.

Lentz, D. L.; Hamilton, T. L.; Dunning, N. P..; Scarborough, V. L.; Luxton, T. P.; Vonderheide, A. P.; Tepe, E. J.; Perfetta, C. J.; Brunemann, J.; Grazioso, L.; Valdez, F.; Tankersley, K. B.; Weiss, A.A. (2020).  Molecular genetic and geochemical assays reveal severe contamination of drinking water reservoirs at the ancient Maya city of Tikal.  Scientific Reports, 10, 10316-10326.

Walsh, M.; Savu, A.; Chatterjee, R.; Vonderheide, A. P. (2019): Investigation of Water-Soluble Silver Ion and Silver Nanoparticles in Wound Dressing Using ICP-MS.  Journal of Analytical and Bioanalytical Techniques, 10, 414.

E. A. Hussein and R. J. White, “Silver Nanoneedle Probes Enable Sustained DC Current, Single-Channel Resistive Pulse Nanopore Sensing,” Anal. Chem. 2021, 93, 11568-11575. 

M. Santos-Cancel, L. W. Simpson, J. B. Leach and R. J. White, "Direct, Real-Time Detection of Adenosine Triphosphate Release from Astrocytes in 3-Dimensional Culture Using an Integrated Electrochemical, Aptamer-Based Sensor", ACS Chem. Neurosci., 2019, 10, 4, 2070–2079. 

K. Sykes and R. J. White, "Effects of Nucleic Acid Structural Heterogeneity on the Electrochemistry of Tethered Redox Molecules." Langmuir, 2022, Just Accepted. 

I. Belmonte and R. J. White“3-D printed microfluidics for rapid prototyping and testing of electrochemical, aptamer-based sensor devices under flow conditions,” Anal. Chim. Acta. 2022, 1192, 339337. 



Vijayan, A. N.; Refaei, M. A.; Silva, R. N.; Tsang, P.; Zhang, P. (2021): Detection of Sortase A and identification of its inhibitors by paramagnetic nanoparticle-assisted nuclear relaxation. Analytical Chemistry, 93, 46, 15430-15437. 

Smith, M. E.; Rose, D. P.; Cui, X.; Stastny, A.; Zhang, P.; Heineman, W. R. (2021): A visual hydrogen sensor prototype for monitoring Magnesium implant biodegradation. Analytical Chemistry, 93, 30, 10487–10494. 

Smith, M. E.; Stastny, A. L.; Lynch, J. A.; Yu, Z.; Zhang, P.; Heineman, W. R. (2020): Indicator dyes and catalytic nanoparticles for irreversible visual hydrogen sensing. Analytical Chemistry, 92, 15, 10651–10658.

Yu, Z.; Grasso, M. F.; Cui, X.; Silva, R. N.; Zhang, P. (2020): Sensitive and label-free SERS detection of single-stranded DNA assisted by silver nanoparticles and gold-coated magnetic nanoparticles.  ACS Applied Bio Materials, 3, 5, 2626-2632. 

Yu, Z.; Grasso, M. F.; Sorensen, H. H.; Zhang, P. (2019): Ratiometric SERS detection of polycyclic aromatic hydrocarbons in soil assisted by β-cyclodextrin modified gold nanoparticles. Microchim Acta., 186, 391-398.