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Katherine Tepperman
Professor, Undergraduate Director
Biological Sciences - Tenure-Track Faculty
833 Rieveschl Hall
513-556-9742
katherine.tepperman@uc.edu
Education
PhD, University of Connecticut, to Present.
Research Interests
My main research interest concerns metal-based drugs and the use of cell culture models in determination of mechanism of action. We have been studying gold-based drugs used to treat rheumatoid arthritis for a number of years and have identified specific gold containing metabolites in patient fluids. We are now studying the interaction of these metabolites with cultured cells and have recently begun studies aimed at determining whether any of these metabolites can inhibit replication of the AIDS virus.
Peer Reviewed Publications
Vonderheide, A., Meija, J., Tepperman, K., Puga, A., Pinhas, A., States, C., & Caruso, J. (2004). Retention of Cr(III) by high performance chelation ion chromatography interfaced to inductively coupled plasma mass spectrometric detection with collision cell. J. Chromatog. A , 1024, 129-137.
Wei, Y., Tepperman, K., Huang, M., Sartor, M., & Puga, A. (2004). Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin. J. Biochem., 279, 4110-4119.
